- funded by IMI-JU
- 01 March 2011 - 31 August 2016
- 11 EFPIA members
- 10 Academia and 5 SME's
- Total cost € 23,032,609
Visual timeline of the project activities, giving you insight in the public releases of DDMoRe outcomes like documents, specifications, prototypes, demonstrators and courses.
Tumor Growth Inhibition models
An estimation-simulation study with the Simeoni model Predictive PK-PD modelling of tumor growth after administration of a cytotoxic drugs as single-...
An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment.
Model used (Friberg et al. CPT, 2009)...
Model-informed drug discovery and development online course to illustrate the principles of cardiac safety in drug discovery and development. This includes consideration on preclinical,...
Online course material on antibiotics and bacterial infections adapted from the Infectious disease course in model-informed drug development.
The material includes a brief background to the...
Drug Combinations in Oncology, Rocchetti Tumor Growth Inhibition model
Predictive PK-PD modelling of tumor growth after administration of antiangiogenic and cytotoxic drugs, as...
Aim
The Drug Disease Model Resources (DDMoRe) Repository has been developed to enable access to curated and shared knowledge for...
The DDMoRe consortium concludes the series of comprehensive face-to-face courses with the first advanced course introducing the principles of model-informed drug development, covering a range of...
This DDMoRe course in Infectious Diseases is one in a series of comprehensive face-to-face courses introducing the principles of model-informed drug development, covering a range...
This Pharma lead DDMoRe course in Cardiac Safety evaluation is one in a series of comprehensive face-to-face courses introducing the principles of model-informed...
The Beta-release of the Interoperability Framework is available now for download.
A high-level overview of the features...
MDL is a human writeable and human readable language designed to describe pharmacometric models. It is intended to be largely agnostic about...
DDMoRe consortium continues a series of comprehensive face-to-face courses introducing the principles of model-informed drug development, covering a range of...
Simulx is a function of the R package mlxR. Simulx allows one to simulate complex models for longitudinal data by interfacing the C++ MlxLibrary with R.
...
The first public DDMoRe course launches a series of comprehensive face-to-face courses introducing the principles of model-informed drug development, covering a range of...
Pharmacometric Markup Language (PharmML)
XML based format, PharmML for storing...
Simulx is a function of the R package mlxR. Simulx allows one to simulate complex models for longitudinal data by interfacing the C++ MlxLibrary with R.
...
The Model Repository from the Drug Disease Model Resources (...
The Pharmacometrics Group at Uppsala University has hosted the first DDMoRe course to PhD students and postdoctoral fellows.
...
7th Noordwijkerhout Symposium on Pharmacokinetics, Pharmacodynamics and Systems Pharmacology, Noordwijk, 2014
DDMoRe was running a 2 hours hands-on...
MDL-IDE
The Modelling Description Language (MDL) is a human writeable and human readable language to express the information required to describe pharmacometric models and...
PharmML
PharmML stands for Pharmacometrics Markup Language. This is the first public release of a new standard for encoding of models, associated tasks and their annotation...