ProbOnto is a knowledge base and ontology of probability distributions. It was designed to facilitate the encoding of nonlinear-mixed effect models and their annotation in PharmML developed by DDMoRe... Read more
The interoperable Modelling Markup Languages (MMLs) will provide the representation standards and ontologies of the data and associated metadata. These MMLs will be based on existing languages and will be evaluated for their interoperability with developed and considered clinical (CDISC) and pharmaceutical (PISTOIA alliance) standards.
Main outcome of WP4
ProbOnto is a knowledge base and ontology of probability distributions. It was designed to facilitate the encoding of nonlinear-mixed effect models and their annotation in PharmML developed by DDMoRe... Read more
Leiden, The Netherlands, 22nd of August 2016 – The Modelling & Simulation community is poised to benefit from the first fully integrated open-source modelling environment, proudly released by the... Read more
Standard Output (SO) SO is a tool-independent exchange XML-based format, intended for storage of results in standardised form. It enables effective data exchange within complex workflows as well as... Read more
Location: GSK House, 980 Great West Rd, Brentford, London, Middlesex TW8 9GS Date: 17th March (from 12:00) – 18th March (until last man standing)https://goo.gl/maps/N3qqgsr9rkq Transport links from... Read more
Leiden, The Netherlands, 3rd of June 2015 – PharmML, a flexible format for exchanging computational models in pharmaceutical R&D, opens new opportunities for drug discovery and clinical research... Read more
Pharmacometric Markup Language (PharmML) XML based format, PharmML for storing and exchange of pharmacometrics models and associated results. PharmML provides means to encode - mathematical/... Read more
Biophysical constraints on the evolution of tissue structure and function. P. J. Hunter and B. de Bono Abstract Phylogenetic analyses based on models of molecular sequence evolution have driven to... Read more
Leiden, the Netherlands, 20th December 2013 – The IMI Drug Disease Model Resources (DDMoRe) consortium is launching modelling languages to enable quantitative decision making across all stages of... Read more
October 30-31 2013, Brussels, Belgium The workshop is jointly organised by partners on IMI projects DDMoRe, OpenPHACTS and eTox, and hosted by the Innovative Medicines Initiative (IMI). This event... Read more
Functional tissue units and their primary tissue motifs in multi-scale physiology. Bernard de Bono, Pierre Grenon, Richard Baldock, Peter Hunter JBiomedSemantics Abstract Background Histology... Read more
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Support was received from the Innovative Medicines Initiative Joint Undertaking under grant agreement n° 115156, resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution. The DDMoRe project is also financially supported by contributions from Academic and SME partners