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Are the components of the framework any use outside of the system?

The DDMoRe R package can in principle also be used in R scripts outside of the Interoperability Framework, but several of the functions in the package rely on services that are only available within the system, so it may be of limited use.
The converter toolbox for converting models to and from PharmML can also be used outside of the Interoperability Framework via a command-line interface.