Interoperability Framework

DDMoRe, sharing knowledge to improve drug development

The Drug Disease Model Resources (DDMoRe) consortium has been created to improve the quality, efficiency and cost effectiveness of Model-Informed Drug Discovery & Development.

In model-informed drug development, information from a wide array of sources can be integrated into models to describe and predict the behavior of complex disease/biological systems and drug actions. The consortium will deliver a platform as resource for models and knowledge sharing, based on standards to ensure consistency of evidence. Academia, industries and health authorities can rely on this platform in making decisions about development, approval of new medicines and improvement of therapy with existing drugs.

DDMoRe’s products

DDMoRe’s products deliver an open source, integrated framework to enable Model-Informed Drug Discovery & Development:

Access to curated and shared knowledge

Bridging modelling tools and methodologies

Support adoption of repository and framework

Model-informed Drug Discovery and Development in Cardiac Safety

This public Pharma lead DDMoRe course in Cardiac Safety evaluation is one in a series of comprehensive face-to-face courses introducing the principles of model-informed drug discovery and development, covering a range of therapeutic areas, via the newly-developed DDMoRe interoperability framework. The Department of Quantitative Clinical Pharmacology, AstraZeneca R&D Gothenburg, Sweden...

Read more