- funded by IMI-JU
- 01 March 2011 - 28 February 2016
- 10 EFPIA members
- 10 Academia and 6 SME's
- Total cost € 21,165,061
The Drug Disease Model Resources (DDMoRe) consortium builds and maintains a universally applicable, open source, model based framework, intended as the gold standard for future collaborative drug and disease Modelling & Simulation.
Modelling and Simulation (M&S) is a technology providing the quantitative basis for informed decision making across all stages of pharmaceutical drug development. This model-based drug development is accepted as a vital approach in understanding patients’ drug-related benefit and risk. Information from a wide array of sources to describe and predict the behaviours of complex disease/biological systems and drug actions can be integrated in models.
Before the DDMoRe consortium, a lack of common tools, languages and ontologies for M&S limited the access to stored information which created significant gaps in the way knowledge could be exploited within drug development. The DDMoRe consortium is generating a public drug and disease model repository as well as an open source interoperability framework containing standards and tools to cover the identified gaps in the M&S software ecosystem. The DDMoRe project’s standards and tools – intended as the gold standard for future collaborative drug and disease M&S - will be supported by comprehensive training and will be made publicly accessible.
- Enable efficient exchange and integration of modelling activities.
- Outputs across software tools, disciplines and departments within and among organizations.
- Provide standards applicable to all areas of M&S, appropriate for adoption and use by all relevant domain stakeholders.
- Development of an open, publicly available, free-to-use model repository, based on the developed standards, to promote the re-use of models.
- The model repository may evolve into a global reference for model-based efforts in the therapeutic areas Diabetes, Oncology and Other Diseases.
- Provide support for education and training in drug/disease M&S.