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DDMoRe Project Timeline

2016

Oct 27

Tumor Growth Inhibition models
An estimation-simulation study with the Simeoni model Predictive PK-PD modelling of tumor growth after administration of a cytotoxic drugs as single-...

Start date: Oct 27 2014
End date: Oct 27 2016
Oct 27

An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment.

Model used (Friberg et al. CPT, 2009)...

Start date: Mar 27 2014
End date: Oct 27 2016
Oct 27

Model-informed drug discovery and development online course to illustrate the principles of cardiac safety in drug discovery and development. This includes consideration on  preclinical,...

Start date: Mar 27 2014
End date: Oct 27 2016
Oct 27

Online course material on antibiotics and bacterial infections adapted from the Infectious disease course in model-informed drug development.
The material includes a brief background to the...

Start date: Mar 27 2014
End date: Oct 27 2016
Oct 27

Drug Combinations in Oncology, Rocchetti Tumor Growth Inhibition model
Predictive PK-PD modelling of tumor growth after administration of antiangiogenic and cytotoxic drugs, as...

Start date: Mar 27 2014
End date: Oct 27 2016
Aug 22

The official release of the Interoperability Framework is now available for download.
 
Supported features...

Start date: Aug 22 2016
End date: Aug 22 2016
Aug 22

Aim
The Drug Disease Model Resources (DDMoRe) Repository has been developed to enable access to curated and shared knowledge for...

Start date: Aug 22 2016
End date: Aug 22 2016
Jul 08

The DDMoRe consortium concludes the series of comprehensive face-to-face courses with the first advanced course introducing the principles of model-informed drug development, covering a range of...

Start date: Jul 04 2016
End date: Jul 08 2016
Feb 08

This DDMoRe course in Infectious Diseases is one in a series of comprehensive face-to-face courses introducing the principles of model-informed drug development, covering a range...

Start date: Feb 08 2016
End date: Feb 08 2016
Jan 18

This Pharma lead DDMoRe course in Cardiac Safety evaluation is one in a series of comprehensive face-to-face courses introducing the principles of model-informed...

Start date: Jan 18 2016
End date: Jan 18 2016
 

2015

Dec 11

Model Description Language

MDL is a human writeable and human readable language designed to describe pharmacometric models. It is intended to be largely agnostic about...

Start date: Dec 11 2015
End date: Dec 11 2015
Dec 11

The Beta-release of the Interoperability Framework is available now for download.
 

Supported features

A high-level overview of the features...

Start date: Dec 11 2015
End date: Dec 11 2015
Jul 27

DDMoRe consortium continues a series of comprehensive face-to-face courses introducing the principles of model-informed drug development, covering a range of...

Start date: Jul 27 2015
End date: Jul 27 2015
Apr 29

Simulx is a function of the R package mlxR. Simulx allows one to simulate complex models for longitudinal data by interfacing the C++ MlxLibrary with R.

...

Start date: Apr 29 2015
End date: Apr 29 2015
Mar 16

The first public DDMoRe course launches a series of comprehensive face-to-face courses introducing the principles of model-informed drug development, covering a range of...

Start date: Mar 16 2015
End date: Mar 16 2015
Feb 06

Pharmacometric Markup Language (PharmML)
XML based format, PharmML for storing...

Start date: Feb 06 2015
End date: Feb 06 2015
Jan 20

Simulx is a function of the R package mlxR. Simulx allows one to simulate complex models for longitudinal data by interfacing the C++ MlxLibrary with R.

...

Start date: Jan 20 2015
End date: Jan 20 2015
 

2014

Oct 31

The Model Repository from the Drug Disease Model Resources (...

Start date: Mar 01 2011
End date: Oct 31 2014
Aug 22

Model-Based Drug Development in Diabetes.

The Pharmacometrics Group at Uppsala University has hosted the first DDMoRe course to PhD students and postdoctoral fellows.

 

...

Start date: Aug 18 2014
End date: Aug 22 2014
Jun 09

Simulx is an R function for easily computing predictions and simulating data from both Mlxtran and PharmML models.
 

Simulx is...

Start date: Mar 01 2011
End date: Jun 09 2014
Apr 23

7th Noordwijkerhout Symposium on Pharmacokinetics, Pharmacodynamics and Systems Pharmacology, Noordwijk, 2014

DDMoRe was running a 2 hours hands-on...

Start date: Apr 23 2014
End date: Apr 23 2014
 

2013

Nov 28
The MDL IDE

MDL-IDE

The Modelling Description Language (MDL) is a human writeable and human readable language to express the information required to describe pharmacometric models and...

Start date: Mar 01 2011
End date: Nov 28 2013
Nov 11

PharmML
PharmML stands for Pharmacometrics Markup Language. This is the first public release of a new standard for encoding of models, associated tasks and their annotation...

Start date: Mar 01 2011
End date: Nov 11 2013